Biparatopic sybodies neutralize SARS-CoV-2 variants of concern and mitigate drug resistance

In collaboration with Markus Seeger's lab (University of Zurich) and Cristina Paulino's lab (University of Groningen), we rationally engineered biparatopic and multivalent synthetic nanobodies neutralizing SARS-CoV-2 and variants of concern.

https://pubmed.ncbi.nlm.nih.gov/35253970/

Funding : SNF-NRP78 #4078P0_198314