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Latest Achievments
The Roles of the 5′ and 3′ Untranslated Regions in Human Astrovirus Replication06.07.2023The Roles of the 5′ and 3′ Untranslated Regions in Human Astrovirus Replication. Wildi N, Seuberlich T. Viruses. 2023; 15(6):1402. https://doi.org/10.3390/v15061402 Nicole Wildi’s main paper for her PhD project addressing molecular aspects of astrovirus replication is out now!
Archival wild-type poliovirus 1 infected central nervous system tissues of the pre-vaccination era in Switzerland reveal a distinct virus genotype06.07.2023We sequenced coding-complete poliovirus 1 genomes in 70-years old historical tissues of two patients with poliomyelitis and found new insights into the viral diversity during the last poliovirus epidemic in Switzerland. Archival wild-type poliovirus 1 infected central nervous system tissues of the pre-vaccination era in Switzerland reveal a distinct virus genotype Wildi N, Bagatella S, Koch MC, Oevermann A, Seuberlich T. Acta Neuropathol. 2023 Mar;145(3):357-359. doi: 10.1007/s00401-023-02545-5
LRP6 Is a Functional Receptor for Attenuated Canine Distemper Virus09.03.2023In collaboration with Sven Rottenberg's lab (University of Bern), using a genome-wide CRISPR/Cas9 knockout screen, we discovered LRP6 as a functional receptor for the CDV Onderstepoort attenuated strain.
